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Una oreja impresa en 3D hecha de células humanas fue trasplantada a una mujer

June 2, 2022
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Una oreja impresa en 3D hecha de células humanas fue trasplantada a una mujer


Imagen de 3DBio Therapeutics

Un hombre de 20 años una mexicana que ha tenido una micro oreja toda su vida por fin es una grande. Los científicos imprimieron en 3D una nueva oreja para ella, construida a partir de sus propias células, y completaron el trasplante como parte de un “primer ensayo clínico en humanos”.

El implante, siete años en desarrollo, fue desarrollado por Queens 3DBio Therapeutics. Se hizo para alinearse simétricamente con la oreja izquierda de la receptora, Alexa, que quiere ser conocida solo por su nombre de pila.

Alexa nació con microtia, una condición rara que resulta en un exterior deformado y anormalmente pequeño para el oído. El defecto de nacimiento, o una condición comparable llamada anotia, afecta a unos 1500 bebés en los Estados Unidos cada año, cube 3DBio.

el paciente tenia toda su vida tuvo que llevar el cabello suelto para ocultar su microoreja y está feliz de finalmente experimentar con varios peinados ahora que se ha hecho un trasplante, New York Occasions informes.

Para formar la oreja, Los desarrolladores dividieron una pequeña muestra de las células de la mujer, extraídas de medio gramo de cartílago, en miles de millones de células. El proceso involucra varios pasos que 3DBio no desarrolló para proteger el secreto de sus técnicas patentadas, pero lo que se sabe es que también involucra una tinta segura a base de biocolágeno.


Una de las orejas impresas en 3D que 3DBio creó para las reconstrucciones. Imagen de 3DBio Therapeutics

alexa es una de 11 voluntarios con orejas extremadamente pequeñas o sin orejas que participan en ensayos clínicos de 3DBio. La salud de estas personas, con edades comprendidas entre los seis y los 25 años, será monitoreada durante cinco años para determinar qué tan seguro es el procedimiento, así como para detectar cualquier cambio estético. Debido a que la tecnología es tan nueva, aún no se sabe si las orejas hechas por el hombre serían rechazadas.

Hay una posibilidad al cuerpo le irá bien con la nueva oreja, ya que el apéndice se imprime usando células del cuerpo del paciente.

3DBio pretende documentar su investigación con más detalle en una revista médica en el futuro, aunque en la actualidad mantiene los labios cerrados debido a problemas de propiedad.

Este trasplante puede para ser completado en unas pocas horas fuera de un hospital. Por el contrario, las reconstrucciones típicas de microtia involucran cirugía hospitalaria.

es un gran paso avanzado en el mundo de la ingeniería de tejidos, y las implicaciones son enormes. Este implante de oído podría ser más una adición cosmética, pero con el tiempo, 3DBio anticipa que su tecnología podría avanzar lo suficiente como para reproducir partes más funcionales, como los discos de la columna vertebral o incluso el hígado y los riñones.

[via The New York Times and 3DBio Therapeutics, images via 3DBio Therapeutics]





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