UC Davis Well being researchers have obtained a $5.6 million grant by way of the Coast to Coast Consortium to advance their pioneering work with the Nationwide Institutes of Well being (NIH) All of Us Analysis Program.
The grant is designed to extend participant participation, enrollment, information assortment, and retention. This might be primarily based on the inspiration established by the California Precision Medication Consortium. Established in 2018, the consortium has enrolled greater than 65,500 individuals in this system.
Alexander Borowsky, professor of pathology and laboratory drugs, leads the analysis at UC Davis. He confused the significance of this work.
“The All of Us analysis program provides an unprecedented alternative to incorporate various populations in large-scale genomic analysis,” Borowsky mentioned. “By together with people from traditionally underrepresented communities, we will uncover insights into genetic variations which will have been ignored prior to now, finally resulting in extra equitable healthcare for all.”
ABC Information' Becky Worley is taking part within the Diet for Precision Well being examine, which is a part of the All of Us analysis program.
Funding consists of Precision Diet for Well being
UC Davis can also be one among 14 establishments nationwide receiving funding for the associated examine, Diet for Precision Well being. The analysis investigates customized dietary suggestions to enhance well being and forestall illness. Participation requires registration with All of Us.
“A particular function of the examine,” Borowsky mentioned, “is that individuals are invited to be energetic companions within the analysis course of. This transforms the dynamics of our research. “Their invaluable insights and lived experiences enrich each facet of our work, making certain that our analysis shouldn’t be solely scientifically rigorous but in addition really significant and related to the communities we serve.”
The Coast to Coast Consortium represents a various and dynamic community dedicated to the development of biomedical analysis and innovation.
UC Davis collaborates with different consortium establishments on analysis, together with Yale College, UC San Diego, UC San Francisco, Cedars-Sinai Medical Heart, the College of Southern California, and the Puerto Rico Scientific Analysis Consortium.
“The All of Us analysis program provides an unprecedented alternative to incorporate various populations in large-scale genomics analysis.”—Alexander Borowsky, Professor, Division of Pathology and Laboratory Medication
Greater than 100,000 individuals have obtained customized information
This award follows this system's current achievement of returning customized health-related DNA outcomes to greater than 100,000 individuals.
Returning the outcomes to individuals entails inspecting genes related to critical well being circumstances, comparable to hereditary cancers and coronary heart illness. By this course of, this system noticed 32,500 DNA variants. Greater than 7,000 of those variants had by no means been noticed amongst individuals who had beforehand undergone genetic testing.
By offering individuals with actionable info, this system not solely promotes particular person well being outcomes, but in addition contributes to international analysis efforts in genomic drugs.
Recruitment for All of Us at UC Davis Well being is ongoing. Volunteers have to be not less than 18 years previous and will be of any well being standing, gender, race, ethnicity or cultural background. Contributors are invited to an preliminary 30-minute to one-hour in-person go to, with common on-line well being and life-style updates within the months and years to observe.
Numerous and complete information drives analysis
Greater than 800,000 individuals have joined All of Us to contribute to this analysis effort. They share a variety of knowledge from organic samples, survey responses, bodily measurements, digital medical data, and wearable units.
These information are made out there to registered researchers by way of this system's Researcher Workbench, furthering biomedical analysis discoveries and selling well being fairness.
Greater than 75% of All of Us individuals establish with communities traditionally underrepresented in medical analysis, whereas about 45% establish with a racial or ethnic minority group.
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The All of Us Analysis Program Coast to Coast Consortium is funded by NIH award OT2OD037644. All of Us is a registered service mark of the U.S. Division of Well being and Human Providers.